The tendency of a compound to interact with other compounds is taken into consideration by most people who have the habit of taking pharmaceutical drugs for treating health conditions. The use of cannabis in treatment methods has made it possible for people to take advantage of this. Nevertheless, the level of effectiveness of cannabidiol (CBD) medications when it is taken in conjunction with other medications is unclear.
As natural CBD comes with a lot of benefits to humans, it might also have the possibility for it to interact with other pharmaceutical drugs. This is why it is important to know the differences between the additive and synergistic effects of the compounds a person consumes.
Natural CBD products that are effectively used in treating a variety of health conditions and diseases interact with the endocannabinoid system (ECS) of a person. Several studies and researches have come with shreds of evidence that support the statement that the interaction of cannabidiol oil with other pharmaceutical drugs could improve the metabolism of a person and also reduce the resistance of insulin. For instance, CBD oil when consumed for treating anxiety has the potential to improve the control of blood sugar.
A few studies that were conducted in the past have also pointed out that cannabidiol users showed low rates of obesity and diabetes when compared to people who do not use CBD. The result of these studies shows that CBD might have the chance to work effectively with other drugs and yield positive results on interaction.
Opioids Addiction and Cannabidiol
The popular study conducted by Dr. Donald Abrams – an Oncologist from San Francisco – during the year 2011 showed that subjects exposed to cannabis showed no major changes in the concentration of opioid blood level. When the cannabis administration was followed, patients reported a reduction of pain by 27 percent. This has pointed out the safe augmentation of the pain-relieving effects of opioids when they interact with CBD.
In addition to all these findings, the study has also proved that a combination of CBD and opioids used was effective in treating people who were having low opioid levels; it was also helpful in reducing the side effects and risks of dependency.
Cytochrome P450 and Cannabidiol
Cytochrome P450 is a necessary enzyme that plays a major role in the interaction of drugs with the human body. One of the main benefits of CBD oil is its non-addictive and safe nature. The enzyme can also interact with other drugs in some patients who take medications for treating epilepsy and seizure as there can be a major interplay between cannabidiol and Cytochrome P450.